STUDY |
SPONSOR |
DESCRIPTION / PURPOSE |
STATUS |
| IMPROVE-IT |
Schering-Plough |
Double-blind randomized study to establish the clinical
benefit and safety of Vytorin vs. Simvastatin Monotherapy
in high risk subjects presenting with ACS |
Enrolling |
| RE-LY |
Boehringer Ingelheim |
Randomized Evaluation of long term anticoagulant therapy
comparing the efficacy and safety of two blinded doses of
dabigatran etexilate with open label warfarin for the prevention
of stroke in patients with non-valvular atrial fibrillation |
Enrolling |
| RIGHT |
Guidant |
Head to head trial Comparing Guidant Rhythm ID to Medronic
Wavelet by classifying all appropriate and inappropriate detections
of VT/VF events in patients receiving a new or replacement
ICD |
Enrolling |
| PEGASUS-CRT |
Guidant |
Demonstrate the benefit of atrial-synchronized bi-ventricular
pacing by randomizing patients implanted with a Guidant CRT
device to one of 3 arms: DDD-70, DDD-40, or DDR-40. |
Enrolling |
| SAVE PACe |
Medtronic |
Determine the effect of Search AV and MVP algorithm on the
reduction of ventricular pacing and cardiovascular function
in patients implanted with a new pacemaker. |
Enrolling |
| REDUCE |
St. Jude |
Determine the benefit of using AutoIntrinsic Conduction
Search vs. a programmed AV delay in patients implanted with
a St. Jude ICD (with AICS) who are paced in the RV<
25% of the time |
Enrolling |
| MVP |
Medtronic |
Determine benefit from Managed Ventricular Pacing compared
to VVI 40 pacing in patients implanted with a new Medtronic
dual chamber ICD |
Follow-up Phase |
| ACT Registry |
St. Jude |
Registry of all patients implanted with a St. Jude Medical
ICD/CRT. Purpose: Evaluate the utilization of advanced features
in patients with current ICD indication |
Follow-up Phase |
| MASTER |
Medtronic |
A Medtronic ICD trial testing the effectiveness of Microvolt
T Wave Alternans Testing utilized for risk stratification
of post MI patients |
Follow up Phase |
| IMPROVE-HF |
Medtronic |
Registry to improve the use of Evidence-based heart failure
therapies in the outpatient setting. Medical records of patients
with previous diagnosis of MI or HF will be reviewed in the
office by Access Medical |
Active |
| APPRAISE |
Bristol-Myers Squibb |
A phase 2, Placebo-Controlled, Randomized, Double-blind,
Parallel arm, dose ranging study to evaluate safety and efficacy
of Apixaban in patients with a recent acute coronary syndrome |
Enrolling |
| Navigator |
Novartis |
Randomized, double-blind, placebo-controlled, forced titration
study of the efficacy and safety of long term administration
of Nateglinide and Valsartan in the prevention of diabetes
and cardiovascular outcomes in subjects with impaired glucose
tolerance. |
Follow-up Phase |
| MENDMI |
Guidant/Boston Scientific |
Feasibility study (IDE-B) to assess the safety and preliminary
effects of pacing therapy on the left ventricular enlargement
and dilatation, in patients at high risk of severe post-MI
remodeling |
Enrolling |
